Interleukin-35-mediated induction of a novel regulatory T cell population

Regulatory T cells (T(regs)) play a critical role in the maintenance of immunological self-tolerance. Naïve human or murine T cell treatment with the inhibitory cytokine IL-35 induces a regulatory population, termed iT(R)35, that mediates suppression via IL-35, but not IL-10 or TGFβ, neither express...

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Autores principales: Collison, Lauren W., Chaturvedi, Vandana, Henderson, Abigail L., Giacomin, Paul R., Guy, Cliff, Bankoti, Jaishree, Finkelstein, David, Forbes, Karen, Workman, Creg J., Brown, Scott A., Rehg, Jerold E., Jones, Michael L., Ni, Hsiao-Tzu, Artis, David, Turk, Mary Jo, Vignali, Dario A. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008395/
https://ncbi.nlm.nih.gov/pubmed/20953201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1952
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