Interleukin-35-mediated induction of a novel regulatory T cell population

Regulatory T cells (T(regs)) play a critical role in the maintenance of immunological self-tolerance. Naïve human or murine T cell treatment with the inhibitory cytokine IL-35 induces a regulatory population, termed iT(R)35, that mediates suppression via IL-35, but not IL-10 or TGFβ, neither express...

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Detalhes bibliográficos
Main Authors: Collison, Lauren W., Chaturvedi, Vandana, Henderson, Abigail L., Giacomin, Paul R., Guy, Cliff, Bankoti, Jaishree, Finkelstein, David, Forbes, Karen, Workman, Creg J., Brown, Scott A., Rehg, Jerold E., Jones, Michael L., Ni, Hsiao-Tzu, Artis, David, Turk, Mary Jo, Vignali, Dario A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008395/
https://ncbi.nlm.nih.gov/pubmed/20953201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1952
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