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NKG2D is Required for NK Cell Activation and Function in Response to E1-deleted Adenovirus
Despite the high transduction efficiency in vivo, the application of recombinant E1-deleted adenoviral vectors for in vivo gene therapy has been limited by the attendant innate and adaptive immune responses to adenoviral vectors. Natural killer (NK) cells have been shown to play an important role in...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008345/ https://ncbi.nlm.nih.gov/pubmed/21076062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002771 |
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