Identification of a novel germline missense mutation of the androgen receptor in African American men with familial prostate cancer

Race, family history and age are the unequivocally accepted risk factors for prostate cancer (PCa). Androgen receptor (AR)-dependent signaling is an important element in prostate carcinogenesis and its progression to metastatic disease. We examined the possibility of genomic changes in the AR in ass...

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Main Authors: Hu, Si-Yi, Liu, Tao, Liu, Zhen-Zhen, Ledet, Elisa, Velasco-Gonzalez, Cruz, Mandal, Diptasri M, Koochekpour, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008322/
https://ncbi.nlm.nih.gov/pubmed/20173765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.5
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