Identification of a novel germline missense mutation of the androgen receptor in African American men with familial prostate cancer

Race, family history and age are the unequivocally accepted risk factors for prostate cancer (PCa). Androgen receptor (AR)-dependent signaling is an important element in prostate carcinogenesis and its progression to metastatic disease. We examined the possibility of genomic changes in the AR in ass...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hu, Si-Yi, Liu, Tao, Liu, Zhen-Zhen, Ledet, Elisa, Velasco-Gonzalez, Cruz, Mandal, Diptasri M, Koochekpour, Shahriar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008322/
https://ncbi.nlm.nih.gov/pubmed/20173765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.5
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