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Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration
Neurosteroids hold great promise for the treatment of diseases of the central nervous system (CNS). We compared the uptake by 11 brain regions and appearance in blood of tritium-labeled pregnenolone and progesterone after intranasal and intravenous (IV) injection. Both neurosteroids appeared in bloo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008321/ https://ncbi.nlm.nih.gov/pubmed/20570588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.05.033 |
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