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STRUCTURE-GUIDED IDENTIFICATION OF A LAMININ BINDING SITE ON THE LAMININ RECEPTOR PRECURSOR

The 37/67 kDa human laminin receptor (LamR) is a cell surface receptor for laminin, prion protein, and a variety of viruses. Because of its wide range of ligands, LamR plays a role in numerous pathologies. LamR overexpression correlates with a highly invasive cell phenotype and increased metastatic...

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Détails bibliographiques
Auteurs principaux: Jamieson, Kelly V., Hubbard, Stevan R., Meruelo, Daniel
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008175/
https://ncbi.nlm.nih.gov/pubmed/21040730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.028
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