Site-directed mutagenesis and structural interpretation of the nidogen binding site of the laminin gamma1 chain.

A precise molecular map of the nidogen binding site of laminins was obtained by site-directed mutagenesis and structural analysis of the 56 residue LE module gamma1III4 of their gamma1 chain. This demonstrated the crucial importance of the sequence DPNAV (position 800-804) in the disulfide-bonded lo...

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Main Authors: Pöschl, E, Mayer, U, Stetefeld, J, Baumgartner, R, Holak, T A, Huber, R, Timpl, R
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC452258/
https://ncbi.nlm.nih.gov/pubmed/8895559
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