Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2

We report here a novel role for Jun dimerization protein-2 (JDP2) as a regulator of the progression of normal cells through the cell cycle. To determine the role of JDP2 in vivo, we generated Jdp2-knockout (Jdp2KO) mice by targeting exon-1 to disrupt the site of initiation of transcription. The epid...

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Autors principals: Pan, J, Nakade, K, Huang, Y-C, Zhu, Z-W, Masuzaki, S, Hasegawa, H, Murata, T, Yoshiki, A, Yamaguchi, N, Lee, C-H, Yang, W-C, Tsai, E-M, Obata, Y, Yokoyama, K K
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007677/
https://ncbi.nlm.nih.gov/pubmed/20802531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.355
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