JDP2 (Jun Dimerization Protein 2)-deficient Mouse Embryonic Fibroblasts Are Resistant to Replicative Senescence

JDP2 (Jun dimerization protein 2, an AP-1 transcription factor) is involved in the regulation of the differentiation and proliferation of cells. We report here that JDP2-deficient mouse embryonic fibroblasts (Jdp2(-/-) MEF) are resistant to replicative senescence. In the absence of JDP2, the level o...

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Autori principali: Nakade, Koji, Pan, Jianzhi, Yamasaki, Takahito, Murata, Takehide, Wasylyk, Bohdan, Yokoyama, Kazunari K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Transcription, Chromatin, and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667768/
https://ncbi.nlm.nih.gov/pubmed/19233846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808333200
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