Suppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1

In a previous study it was found that the therapeutic effects of QLT0267, a small molecule inhibitor of integrin-linked kinase (ILK), were influenced by Her2/neu expression. To understand how inhibition or silencing of ILK influences Her2/neu expression, Her2/neu signaling was evaluated in six Her2/...

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Main Authors: Kalra, J, Sutherland, B W, Stratford, A L, Dragowska, W, Gelmon, K A, Dedhar, S, Dunn, S E, Bally, M B
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2010
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007675/
https://ncbi.nlm.nih.gov/pubmed/20838384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.366
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