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Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice via S1P(1) receptor activation

Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine 1-phosphate (S1P) levels. Furthermore, exogenous sphinga...

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Bibliografiske detaljer
Main Authors: Park, Sang Won, Kim, Mihwa, Chen, Sean W. C., Brown, Kevin M., D’Agati, Vivette D., Lee, H. Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007623/
https://ncbi.nlm.nih.gov/pubmed/20458275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.102
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