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Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice via S1P(1) receptor activation

Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine 1-phosphate (S1P) levels. Furthermore, exogenous sphinga...

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Detalhes bibliográficos
Main Authors: Park, Sang Won, Kim, Mihwa, Chen, Sean W. C., Brown, Kevin M., D’Agati, Vivette D., Lee, H. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007623/
https://ncbi.nlm.nih.gov/pubmed/20458275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.102
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