Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120

Neutralizing antibodies (Nabs) are thought to play an important role in prevention and control of HIV-1 infection and should be targeted by an AIDS vaccine. It is critical to understand how HIV-1 induces Nabs by analyzing viral sequences in both tested viruses and sera. Neutralization susceptibility...

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Hauptverfasser: Kirchherr, Jennifer L, Hamilton, Jennifer, Lu, Xiaozhi, Gnanakaran, S, Muldoon, Mark, Daniels, Marcus, Kasongo, Webster, Chalwe, Victor, Mulenga, Chanda, Mwananyanda, Lawrence, Musonda, Rosemary M, Yuan, Xing, Montefiori, David C, Korber, Bette T, Haynes, Barton F, Gao, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007099/
https://ncbi.nlm.nih.gov/pubmed/21036380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.09.031
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