Unique Mutational Patterns in the Envelope α2 Amphipathic Helix and Acquisition of Length in gp120 Hypervariable Domains Are Associated with Resistance to Autologous Neutralization of Subtype C Human Immunodeficiency Virus Type 1

Autologous neutralizing antibodies (NAb) against human immunodeficiency virus type 1 generate viral escape variants; however, the mechanisms of escape are not clearly defined. In a previous study, we determined the susceptibilities of 48 donor and 25 recipient envelope (Env) glycoproteins from five...

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Bibliographic Details
Main Authors: Rong, Rong, Gnanakaran, S., Decker, Julie M., Bibollet-Ruche, Frederic, Taylor, Jesse, Sfakianos, Jeffrey N., Mokili, John L., Muldoon, Mark, Mulenga, Joseph, Allen, Susan, Hahn, Beatrice H., Shaw, George M., Blackwell, Jerry L., Korber, Bette T., Hunter, Eric, Derdeyn, Cynthia A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900276/
https://ncbi.nlm.nih.gov/pubmed/17360739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00257-07
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