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N-terminally fusion of Her2/neu to HSP70 decreases efficiency of Her2/neu DNA vaccine
DNA vaccines consisted of tumor-associated antigen (TAA) are well suited for immunotherapy against tumor. The construct can contain TAA fused to an appropriate molecule (biologic adjuvant) to improve the efficacy of anti-tumor immune response. Heat shock protein 70 (HSP70) has been shown to be an ex...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Netherlands
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006617/ https://ncbi.nlm.nih.gov/pubmed/20224916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-010-0175-0 |
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