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Respiratory Virus-induced TLR7 activation controls IL-17 associated Increase in mucus via IL-23 regulation: Respiratory virus induced immune environment relies on TLR7-mediated pathways to preserve a non-pathogenic response and regulates IL-17 production

The response to respiratory syncytial virus (RSV), negative strand ssRNA virus, depends upon the ability to recognize specific pathogen associated targets. In the present study the role of TLR7 that recognizes ssRNA was examined. Using TLR7−/− mice we found that the response to RSV infection in the...

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Autors principals: Lukacs, Nicholas W., Smit, Joost J., Nunez, Gabriel, Lindell, Dennis M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006454/
https://ncbi.nlm.nih.gov/pubmed/20624950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000733
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