The Na(+)/Ca(2+) exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia

Chronic intermittent hypoxia (CIH) and cardiovascular dysfunction occur in patients with obstructive sleep apnea. We hypothesized that the Na(+)/Ca(2+) exchanger-1 (NCX1) mediates, at least partially, left ventricular (LV) dysfunction in CIH. Four groups of mice (N = 15–17 per group), either cardiac...

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Bibliografische gegevens
Hoofdauteurs: Chen, Ling, Zhang, Jin, Hu, Xuejiao, Philipson, Kenneth D., Scharf, Steven M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006405/
https://ncbi.nlm.nih.gov/pubmed/20947716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01372.2009
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