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Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival

Transplanted mesenchymal stem cells (MSC) release soluble factors that contribute to cardiac repair and vascular regeneration. We hypothesized that overexpression of GATA-4 enhances the MSC secretome, thereby increasing cell survival and promoting postinfarction cardiac angiogenesis. MSCs harvested...

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Detalhes bibliográficos
Main Authors: Li, Hongxia, Zuo, Shi, He, Zhisong, Yang, Yueting, Pasha, Zeeshan, Wang, Yigang, Xu, Meifeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006287/
https://ncbi.nlm.nih.gov/pubmed/20870802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00557.2010
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