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Role of the PI3-kinase signaling pathway in trafficking of the surfactant protein A receptor P63 (CKAP4) on type II pneumocytes

Surfactant protein A (SP-A) plays an important role in the maintenance of lung lipid homeostasis. Previously, an SP-A receptor, P63 (CKAP4), on type II pneumocyte plasma membranes (PM) was identified by chemical cross-linking techniques. An antibody to P63 blocked the specific binding of SP-A to pne...

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Autors principals: Kazi, Altaf S., Tao, Jian-Qin, Feinstein, Sheldon I., Zhang, Li, Fisher, Aron B., Bates, Sandra R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006267/
https://ncbi.nlm.nih.gov/pubmed/20870746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00372.2009
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