SPINAL CORD MECHANISMS MEDIATING BEHAVIORAL HYPERALGESIA INDUCED BY NEUROKININ-1 TACHYKININ RECEPTOR ACTIVATION IN THE ROSTRAL VENTROMEDIAL MEDULLA

Hyperalgesia in animal injury models is linked to activation of descending raphespinal modulatory circuits originating in the rostral ventromedial medulla (RVM). A neurokinin-1 (NK-1) receptor antagonist microinjected into the RVM before or after inflammation produced by complete Freund’s adjuvant (...

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Detalles Bibliográficos
Main Authors: Lagraize, S. C., Guo, W., Yang, K., Wei, F., Ren, K., Dubner, R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006078/
https://ncbi.nlm.nih.gov/pubmed/20888891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.09.040
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