Cellular and humoral immunity are synergistic in protection against types A and B Francisella tularensis

Herein we report studies with a novel combination vaccine that, when administered to mice, conferred protection against highly virulent strains of Francisella tularensis by stimulating both arms of the immune system. Our earlier studies with Ft.LVS::wbtA, an O-polysaccharide (OPS)–negative mutant de...

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Detalhes bibliográficos
Main Authors: Sebastian, Shite, Pinkham, Jessica T., Lynch, Jillian G., Ross, Robin A., Reinap, Barbara, Blalock, LeeAnn T., Conlan, J. Wayne, Kasper, Dennis L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005699/
https://ncbi.nlm.nih.gov/pubmed/19022323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.10.079
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