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Reconstruction of rat retinal progenitor cell lineages in vitro reveals a surprising degree of stochasticity in cell fate decisions

In vivo cell lineage-tracing studies in the vertebrate retina have revealed that the sizes and cellular compositions of retinal clones are highly variable. It has been challenging to ascertain whether this variability reflects distinct but reproducible lineages among many different retinal progenito...

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Detalhes bibliográficos
Main Authors: Gomes, Francisco L. A. F., Zhang, Gen, Carbonell, Felix, Correa, José A., Harris, William A., Simons, Benjamin D., Cayouette, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005599/
https://ncbi.nlm.nih.gov/pubmed/21148186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.059683
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