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In silico method for inferring genotypes in pedigrees

Our genotype inference method combines sparse marker data from a linkage scan and high-resolution SNP genotypes for several individuals to infer genotypes for related individuals. We illustrate the method’s utility by inferring over 53 million SNP genotypes for 78 children in the Centre d’Etude du P...

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Detalhes bibliográficos
Main Authors: Burdick, Joshua T, Chen, Wei-Min, Abecasis, Gonçalo R, Cheung, Vivian G
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005330/
https://ncbi.nlm.nih.gov/pubmed/16921375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1863
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