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Plexin-A4–semaphorin 3A signaling is required for Toll-like receptor– and sepsis-induced cytokine storm

Plexins and semaphorins are ligand–receptor pairs that serve as guidance molecules in the nervous system and play some roles in immunity. Plexins are similar to the Toll-like receptors (TLRs) in their evolutionary conservation from flies to mammals. By studying plexin-A4–deficient (Plxna4(−/−)) inna...

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Detalhes bibliográficos
Main Authors: Wen, Haitao, Lei, Yu, Eun, So-Young, P.-Y. Ting, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005237/
https://ncbi.nlm.nih.gov/pubmed/21098092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101138
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