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A Conditionally Immortalized Colonic Epithelial Cell Line From A Ptk6 Null Mouse That Polarizes And Differentiates In Vitro

BACKGROUND AND AIMS: PTK6 is an intracellular src-related tyrosine kinase that regulates differentiation in the intestine, where knockout animals have increased proliferative activity and growth characteristics. To explore the phenotype further we attempted to establish epithelial cell lines from th...

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Autori principali: Whitehead, Robert H., Robinson, Pamela. S., Williams, Janice A., Bie, Wenjun, Tyner, Angela. L., Franklin, Jeffrey L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005200/
https://ncbi.nlm.nih.gov/pubmed/18205771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1746.2008.05308.x
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