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Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

Recent studies have shown that oxidative stress contributes to the pathogenesis of muscle damage in dystrophic (mdx) mice. In this study we have investigated the role of NADPH oxidase as a source of the oxidative stress in these mice. The NADPH oxidase subunits gp91(phox), p67(phox) and rac 1 were i...

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Autors principals: Whitehead, Nicholas P., Yeung, Ella W., Froehner, Stanley C., Allen, David G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004864/
https://ncbi.nlm.nih.gov/pubmed/21187957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015354
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