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Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

Recent studies have shown that oxidative stress contributes to the pathogenesis of muscle damage in dystrophic (mdx) mice. In this study we have investigated the role of NADPH oxidase as a source of the oxidative stress in these mice. The NADPH oxidase subunits gp91(phox), p67(phox) and rac 1 were i...

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Bibliografiske detaljer
Main Authors: Whitehead, Nicholas P., Yeung, Ella W., Froehner, Stanley C., Allen, David G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004864/
https://ncbi.nlm.nih.gov/pubmed/21187957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015354
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