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Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

Recent studies have shown that oxidative stress contributes to the pathogenesis of muscle damage in dystrophic (mdx) mice. In this study we have investigated the role of NADPH oxidase as a source of the oxidative stress in these mice. The NADPH oxidase subunits gp91(phox), p67(phox) and rac 1 were i...

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Detalhes bibliográficos
Main Authors: Whitehead, Nicholas P., Yeung, Ella W., Froehner, Stanley C., Allen, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004864/
https://ncbi.nlm.nih.gov/pubmed/21187957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015354
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