Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures

BACKGROUND: Cytokine-induced killer (CIK) cells are typically differentiated in vitro with interferon (IFN)-γ and αCD3 monoclonal antibodies (mAb), followed by the repeated provision of interleukin (IL)-2. It is presently unknown whether thymoglobulin (TG), a preparation of polyclonal rabbit γ immun...

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Autori principali: Bonanno, Giuseppina, Iudicone, Paola, Mariotti, Andrea, Procoli, Annabella, Pandolfi, Annino, Fioravanti, Daniela, Corallo, Maria, Perillo, Alessandro, Scambia, Giovanni, Pierelli, Luca, Rutella, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004824/
https://ncbi.nlm.nih.gov/pubmed/21138560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-129
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