Interleukin-21 induces the differentiation of human umbilical cord blood CD34(-)lineage(- )cells into pseudomature lytic NK cells

BACKGROUND: Umbilical cord blood (UCB) is enriched with transplantable CD34(+ )cells. In addition to CD34-expressing haematopoietic stem cells (HSC), human UCB contains a rare population of CD34(-)lineage(- )cells endowed with the ability to differentiate along the T/NK pathway in response to interl...

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Detalhes bibliográficos
Main Authors: Bonanno, Giuseppina, Mariotti, Andrea, Procoli, Annabella, Corallo, Maria, Scambia, Giovanni, Pierelli, Luca, Rutella, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743656/
https://ncbi.nlm.nih.gov/pubmed/19712464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-46
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