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The Effect of DNA-Dependent Protein Kinase on Adeno-Associated Virus Replication

BACKGROUND: DNA-dependent protein kinase (DNA-PK) is a DNA repair enzyme and plays an important role in determining the molecular fate of the rAAV genome. However, the effect this cellular enzyme on rAAV DNA replication remains elusive. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we charac...

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Detalles Bibliográficos
Main Authors: Choi, Young-Kook, Nash, Kevin, Byrne, Barry J., Muzyczka, Nicholas, Song, Sihong
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004791/
https://ncbi.nlm.nih.gov/pubmed/21188139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015073
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