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New developments in treatment of ovarian carcinoma: focus on trabectedin
Trabectedin is a new marine-derived compound that binds the DNA minor groove and interacts with proteins of the DNA repair machinery. Trabectedin has shown promising single-agent activity in pretreated patients with soft tissue sarcoma, and ovarian and breast cancer, and combination with various oth...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3004573/ https://ncbi.nlm.nih.gov/pubmed/21188115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMR.S9459 |
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