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Trabectedin and its potential in the treatment of soft tissue sarcoma

Trabectedin is a new marine-derived compound that binds the DNA minor groove and interacts with proteins of the DNA repair machinery. Phase I trials have established the standard regimen as 1500 μg/m(2) 24-hour continuous infusion repeated every 3 weeks. Several phase II trials have shown response i...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Cassier, Philippe A, Dufresne, Armelle, Blay, Jean-Yves, Fayette, Jérôme
פורמט: Artigo
שפה:Inglês
יצא לאור: Dove Medical Press 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2503645/
https://ncbi.nlm.nih.gov/pubmed/18728699
תגים: הוספת תג
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