Calcium Binding to PICK1 Is Essential for the Intracellular Retention of AMPA Receptors Underlying Long-Term Depression

NMDA receptor (NMDAR)-dependent long-term depression (LTD) in the hippocampus is mediated primarily by the calcium-dependent removal of AMPA receptors (AMPARs) from the postsynaptic density. The AMPAR-binding, PDZ (PSD-95/Dlg/ZO1) and BAR (Bin/amphiphysin/Rvs) domain-containing protein PICK1 has bee...

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Main Authors: Citri, Ami, Bhattacharyya, Samarjit, Ma, Cong, Morishita, Wade, Fang, Scarlett, Rizo, Josep, Malenka, Robert C.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2010
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004477/
https://ncbi.nlm.nih.gov/pubmed/21147983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4478-10.2010
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