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PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking

Regulation of AMPA receptor (AMPAR) trafficking results in changes in receptor number at the postsynaptic membrane, and hence modifications in synaptic strength, which are proposed to underlie learning and memory. NMDA receptor-mediated postsynaptic Ca(2+) influx enhances AMPAR internalisation, but...

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Detalles Bibliográficos
Autores principales: Hanley, Jonathan G, Henley, Jeremy M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224691/
https://ncbi.nlm.nih.gov/pubmed/16138078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600801
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