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PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking

Regulation of AMPA receptor (AMPAR) trafficking results in changes in receptor number at the postsynaptic membrane, and hence modifications in synaptic strength, which are proposed to underlie learning and memory. NMDA receptor-mediated postsynaptic Ca(2+) influx enhances AMPAR internalisation, but...

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Bibliographic Details
Main Authors: Hanley, Jonathan G, Henley, Jeremy M
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224691/
https://ncbi.nlm.nih.gov/pubmed/16138078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600801
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