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The Nucleotides on the Stem-Loop RNA Structure in the Junction Region of the Hepatitis E Virus Genome Are Critical for Virus Replication

The roles of conserved nucleotides on the stem-loop (SL) structure in the intergenic region of the hepatitis E virus (HEV) genome in virus replication were determined by using Huh7 cells transfected with HEV SL mutant replicons containing reporter genes. One or two nucleotide mutations of the AGA mo...

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Autores principales: Cao, Dianjun, Huang, Yao-Wei, Meng, Xiang-Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004356/
https://ncbi.nlm.nih.gov/pubmed/20943962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01475-10
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