Nodavirus-Induced Membrane Rearrangement in Replication Complex Assembly Requires Replicase Protein A, RNA Templates, and Polymerase Activity

Positive-strand RNA [(+)RNA] viruses invariably replicate their RNA genomes on modified intracellular membranes. In infected Drosophila cells, Flock House nodavirus (FHV) RNA replication complexes form on outer mitochondrial membranes inside ∼50-nm, virus-induced spherular invaginations similar to R...

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Main Authors: Kopek, Benjamin G., Settles, Erik W., Friesen, Paul D., Ahlquist, Paul
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004334/
https://ncbi.nlm.nih.gov/pubmed/20943974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01495-10
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