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Determinants of Tetherin Antagonism in the Transmembrane Domain of the Human Immunodeficiency Virus Type 1 Vpu Protein

Tetherin (BST2/CD317) potently restricts the particle release of human immunodeficiency virus type 1 (HIV-1) mutants defective in the accessory gene vpu. Vpu antagonizes tetherin activity and induces its cell surface downregulation and degradation in a manner dependent on the transmembrane (TM) doma...

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Sonraí Bibleagrafaíochta
Main Authors: Vigan, Raphaël, Neil, Stuart J. D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004320/
https://ncbi.nlm.nih.gov/pubmed/20926557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01699-10
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