Antagonism to and Intracellular Sequestration of Human Tetherin by the Human Immunodeficiency Virus Type 2 Envelope Glycoprotein

Tetherin (CD317/BST-2), an interferon-induced membrane protein, restricts the release of nascent retroviral particles from infected cell surfaces. While human immunodeficiency virus type 1 (HIV-1) encodes the accessory gene vpu to overcome the action of tetherin, the lineage of primate lentiviruses...

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Bibliographic Details
Main Authors: Le Tortorec, Anna, Neil, Stuart J. D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772693/
https://ncbi.nlm.nih.gov/pubmed/19740980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01515-09
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