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Tetherin Restricts Herpes Simplex Virus 1 and Is Antagonized by Glycoprotein M

Tetherin is a broadly active antiviral effector that works by tethering nascent enveloped virions to a host cell membrane, thus preventing their release. In this study, we demonstrate that herpes simplex virus 1 (HSV-1) is targeted by tetherin. We identify the viral envelope glycoprotein M (gM) as h...

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Detalhes bibliográficos
Main Authors: Blondeau, Caroline, Pelchen-Matthews, Annegret, Mlcochova, Petra, Marsh, Mark, Milne, Richard S. B., Towers, Greg J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838283/
https://ncbi.nlm.nih.gov/pubmed/24067975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02250-13
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