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Nbr1 Is a Novel Inhibitor of Ligand-Mediated Receptor Tyrosine Kinase Degradation

Neighbor of BRCA1 (Nbr1) is a highly conserved multidomain scaffold protein with proposed roles in endocytic trafficking and selective autophagy. However, the exact function of Nbr1 in these contexts has not been studied in detail. Here we investigated the role of Nbr1 in the trafficking of receptor...

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Autores principales: Mardakheh, Faraz K., Auciello, Giulio, Dafforn, Tim R., Rappoport, Joshua Z., Heath, John K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004269/
https://ncbi.nlm.nih.gov/pubmed/20937771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00878-10
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