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Nbr1 Is a Novel Inhibitor of Ligand-Mediated Receptor Tyrosine Kinase Degradation

Neighbor of BRCA1 (Nbr1) is a highly conserved multidomain scaffold protein with proposed roles in endocytic trafficking and selective autophagy. However, the exact function of Nbr1 in these contexts has not been studied in detail. Here we investigated the role of Nbr1 in the trafficking of receptor...

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Detalhes bibliográficos
Main Authors: Mardakheh, Faraz K., Auciello, Giulio, Dafforn, Tim R., Rappoport, Joshua Z., Heath, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004269/
https://ncbi.nlm.nih.gov/pubmed/20937771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00878-10
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