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Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in Non Human Primates

Development of a fully effective vaccine against the pre-erythrocytic stage of malaria infection will likely require induction of both humoral and cellular immune responses. Protein based vaccines can elicit such broad-based immunity depending on the adjuvant and how the protein is formulated. Here...

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Bibliografiska uppgifter
Huvudupphovsmän: Tewari, Kavita, Flynn, Barbara J., Boscardin, Silvia B., Kastenmueller, Kathrin, Salazar, Andres M., Anderson, Charles A., Soundarapandian, Velu, Ahumada, Adriana, Keler, Tibor, Hoffman, Stephen L., Nussenzweig, Michel C., Steinman, Ralph M., Seder, Robert A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004225/
https://ncbi.nlm.nih.gov/pubmed/20846528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.08.098
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