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Monitoring Tau-Tubulin Interactions Utilizing Second Harmonic Generation in Living Neurons

Tau is a microtubule associated protein that is localized to the axon in neurons. During pathological conditions including frontotemporal dementia (FTD) a shift in tau isoforms occurs that leads to enhanced expression of a form of tau with four (rather than 3) microtubule binding repeats; this has b...

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Detalhes bibliográficos
Main Authors: Stoothoff, William H., Bacskai, Brian J., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004129/
https://ncbi.nlm.nih.gov/pubmed/19123685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3050422
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