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Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model

Ricin produced by the castor bean plant and Shiga toxins produced by pathogenic Escherichia coli (STEC) and Shigella dysenteriae are type II ribosome inactivating proteins (RIPs), containing an enzymatically active A subunit that inhibits protein synthesis by removing an adenine from the α-sarcin/ri...

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Autori principali: Pierce, Michael, Kahn, Jennifer Nielsen, Chiou, Jiachi, Tumer, Nilgun E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004061/
https://ncbi.nlm.nih.gov/pubmed/21098653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2375411
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