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Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights

Neurokinin-1 receptor blocking has been shown to be beneficial against lung injury in polymicrobial sepsis. In this paper, we evaluated the possible mediators and the mechanism involved. Mice were subjected to cecal ligation and puncture (CLP-) induced sepsis or sham surgery. Vehicle or SR140333 [1 ...

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Detalhes bibliográficos
Main Authors: Hegde, Akhil, Koh, Yung-Hua, Moochhala, Shabbir M., Bhatia, Madhav
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003979/
https://ncbi.nlm.nih.gov/pubmed/21188216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/601098
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