Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights

Neurokinin-1 receptor blocking has been shown to be beneficial against lung injury in polymicrobial sepsis. In this paper, we evaluated the possible mediators and the mechanism involved. Mice were subjected to cecal ligation and puncture (CLP-) induced sepsis or sham surgery. Vehicle or SR140333 [1 ...

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Autors principals: Hegde, Akhil, Koh, Yung-Hua, Moochhala, Shabbir M., Bhatia, Madhav
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003979/
https://ncbi.nlm.nih.gov/pubmed/21188216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/601098
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