Transcutaneous Immunization Studies in Mice Using Diphtheria Toxoid-Loaded Vesicle Formulations and a Microneedle Array

PURPOSE: To determine the immunogenicity of diphtheria toxoid (DT) formulated in two types of vesicles following transcutaneous immunization (TCI) of mice onto microneedle array-treated skin. METHODS: DT-containing cationic liposomes or anionic surfactant-based vesicles were prepared by extrusion an...

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Main Authors: Ding, Zhi, Bal, Suzanne M., Romeijn, Stefan, Kersten, Gideon F. A., Jiskoot, Wim, Bouwstra, Joke A.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2010
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003783/
https://ncbi.nlm.nih.gov/pubmed/20237826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0093-y
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