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Enhanced Infragranular and Supragranular Synaptic Input onto Layer 5 Pyramidal Neurons in a Rat Model of Cortical Dysplasia

Cortical dysplasias frequently underlie neurodevelopmental disorders and epilepsy. Rats with a neonatally induced cortical microgyrus [freeze-lesion (FL)], a model of human polymicrogyria, display epileptiform discharges in vitro. We probed excitatory and inhibitory connectivity onto neocortical pyr...

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Bibliografiske detaljer
Main Authors: Brill, Julia, Huguenard, John R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003588/
https://ncbi.nlm.nih.gov/pubmed/20338974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhq040
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