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Decreased hyperpolarization-activated currents in layer 5 pyramidal neurons enhances excitability in focal cortical dysplasia

Focal cortical dysplasia is associated with the development of seizures in children and is present in up to 40% of intractable childhood epilepsies. Transcortical freeze lesions in newborn rats reproduce many of the anatomical and physiological characteristics of human cortical dysplasia. Rats with...

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Detalles Bibliográficos
Main Authors: Albertson, Asher J., Yang, Jianming, Hablitz, John J.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214088/
https://ncbi.nlm.nih.gov/pubmed/21795624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00164.2011
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