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Decreased hyperpolarization-activated currents in layer 5 pyramidal neurons enhances excitability in focal cortical dysplasia
Focal cortical dysplasia is associated with the development of seizures in children and is present in up to 40% of intractable childhood epilepsies. Transcortical freeze lesions in newborn rats reproduce many of the anatomical and physiological characteristics of human cortical dysplasia. Rats with...
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Formato: | Artigo |
Idioma: | Inglês |
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American Physiological Society
2011
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Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214088/ https://ncbi.nlm.nih.gov/pubmed/21795624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00164.2011 |
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