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Heterodimerization of BAK and MCL-1 Activated by Detergent Micelles
BAK is a key protein mediating mitochondrial outer membrane permeabilization; however, its behavior in the membrane is poorly understood. Here, we characterize the conformational changes in BAK and MCL-1 using detergents to mimic the membrane environment and study their interaction by in vitro pulld...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003418/ https://ncbi.nlm.nih.gov/pubmed/21036904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.144857 |
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