Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION

Crystal structures of the unique hexokinase KlHxk1 of the yeast Kluyveromyces lactis were determined using eight independent crystal forms. In five crystal forms, a symmetrical ring-shaped homodimer was observed, corresponding to the physiological dimer existing in solution as shown by small-angle x...

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Autori principali: Kuettner, E. Bartholomeus, Kettner, Karina, Keim, Antje, Svergun, Dmitri I., Volke, Daniela, Singer, David, Hoffmann, Ralf, Müller, Eva-Christina, Otto, Albrecht, Kriegel, Thomas M., Sträter, Norbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003401/
https://ncbi.nlm.nih.gov/pubmed/20943665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185850
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