Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION

Crystal structures of the unique hexokinase KlHxk1 of the yeast Kluyveromyces lactis were determined using eight independent crystal forms. In five crystal forms, a symmetrical ring-shaped homodimer was observed, corresponding to the physiological dimer existing in solution as shown by small-angle x...

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Main Authors: Kuettner, E. Bartholomeus, Kettner, Karina, Keim, Antje, Svergun, Dmitri I., Volke, Daniela, Singer, David, Hoffmann, Ralf, Müller, Eva-Christina, Otto, Albrecht, Kriegel, Thomas M., Sträter, Norbert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003401/
https://ncbi.nlm.nih.gov/pubmed/20943665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185850
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